منابع مشابه
Engineering of an Artificial Light-Modulated Potassium Channel
Ion Channel-Coupled Receptors (ICCRs) are artificial receptor-channel fusion proteins designed to couple ligand binding to channel gating. We previously validated the ICCR concept with various G protein-coupled receptors (GPCRs) fused with the inward rectifying potassium channel Kir6.2. Here we characterize a novel ICCR, consisting of the light activated GPCR, opsin/rhodopsin, fused with Kir6.2...
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ژورنال
عنوان ژورنال: Israel Journal of Chemistry
سال: 1984
ISSN: 0021-2148
DOI: 10.1002/ijch.198400051